Aim: to investigate the efficacy of PolyGlycopleX on short-term weight loss and associated risk factors in overweight and obese adults.Study design: observational retrospective clinical program analysis.
Subjects: 29 overweight or obese adults (23 women; 6 men), ages 20-65 with a body mass index (BMI) range of 25 kg/m2 to 36 kg/m2 participated in a clinical weight-loss program. 5 g PolyGlycopleX (konjac glucomannan, xanthan gum and sodium alginate) was consumed with 500 mL water, 5-10 minutes before each meal, 2-3 times daily for 14 weeks.
Results: Significant reductions were observed (p less than 0,05) in weight (-5,79 +/-3,55 kg), waist circumference (-12,07 +/-5,56 cm), and percentage body fat (-2,43 +/-2,39 percent) compared to baseline values. In addition, subjects employing PGX had a significant reduction of 19,26 percent (n=17; p less than 0,05) and 25,51 percent (n=16; p less than 0,05) in total and LDL plasma cholesterol values, respectively, at the end of the study period.
Authors’ conclusion: the consumption of PolyGlycopleX (konjac glucomannan, xanthan gum and sodium alginate) in concert with lifestyle modifications may be a useful strategy forweight loss in overweight and obese individuals.